Health effects of low‑level air pollution: implications for public health

Posted on

Image credit: Photo “Friends of the Earth 24” by Friends of the Earth Scotland, Flickr, is licensed under CC by 2.0.

By Brodie Walker

Introduction

In 2022, the Scottish Government commissioned a review to examine whether current levels of ambient air pollution, relatively low by international standards, continue to pose measurable risks to population health. The work was undertaken to inform the Cleaner Air for Scotland 2 (CAFS2) Strategy and support alignment with the World Health Organization’s 2021 Air Quality Guidelines. The review was conducted by an interdisciplinary team from UWE Bristol affiliated with the Air Quality Management Resource Centre and the Centre for Public Health and Wellbeing, and the final report was published in October 2023.

An aim of the review was to assess health impacts in countries with ambient air pollution levels comparable to Scotland. This focus arose from earlier CAFS2 work, which identified an apparent absence of association between air pollution exposure and cardiovascular disease in Scottish studies compared with the wider international evidence. To explore this, we undertook a robust, rapid review examining health effects at low concentrations and potential methodological and contextual explanations for these differences.

Health impacts observed at low levels

The review identified strong and consistent associations between low‑level exposures and a wide range of health outcomes:

  • Cardiovascular disease: Evidence from countries with ambient pollution levels comparable to Scotland indicates increased risks of cardiovascular outcomes, including stroke and ischaemic heart disease, at PM₂.₅ concentrations well below current guideline values. The absence of these findings in the Scottish studies is likely an artefact of study design and data.
  • Respiratory outcomes: Low‑level exposures are associated with worsening asthma, impaired lung development in children, and increased exacerbations of chronic respiratory conditions, even where average concentrations are relatively low.
  • All‑cause mortality: Multiple cohort studies report elevated all‑cause mortality risks across the exposure range, including at the lowest observed concentrations of PM₂.₅.
  • Birth outcomes: Associations with adverse birth outcomes, including preterm birth and low birth weight, have been detected at low NO₂ and PM₂.₅ concentrations, suggesting sensitivity during early life.
  • Neurological and mental health outcomes: Emerging evidence points to associations between long‑term exposure to low‑level air pollution and outcomes such as cognitive decline, dementia, and poorer mental health and well‑being, although causal mechanisms remain an active area of research.
  • Other outcomes: Evidence for outcomes such as diabetes and cancer at low pollution levels is more limited and variable, though observed associations may still be important at a population level.

No evidence of a “safe” threshold

A central finding is the lack of any reliably identifiable threshold at which the harmful effects of air pollution cease. For PM₂.₅, large cohort studies demonstrate linear or near‑linear concentration‑response relationships extending to very low exposure levels. The slope of these associations often remains steep at the lower end of the distribution, indicating that marginal reductions in exposure can still produce public health benefits.

Bus in Edinburgh city centre
“Activists gather to demand clean air as Edinburgh Air Pollution Zone to be expanded.” by Friends of the Earth Scotland is licensed under CC BY 2.0

Low levels of pollution does not mean low inequality

Although national average levels of air pollution in Scotland are relatively low, the review highlights the importance of spatial variability in exposure and the methodological challenges this presents in low‑pollution settings. Limited exposure contrasts and greater potential for exposure misclassification, particularly for traffic‑related pollutants such as PM₂.₅ and NO₂, may reduce the ability of studies to detect associations when analysing population‑level averages. While the review does not explicitly focus on social inequalities, these considerations are consistent with a wider evidence base suggesting that uneven exposure patterns and population vulnerability may contribute to under‑estimation of health effects.

Implications for public health policy

One of the review’s most important implications is that air quality policy remains highly relevant in low‑pollution contexts. Achieving compliance with existing standards should be viewed as a baseline rather than an endpoint.

In Scotland, annual CAFS2 progress reports published in June 2024 and June 2025 confirm continued nationwide compliance with statutory air quality objectives, while recognising that meeting these limits does not imply the absence of health risk (Scottish Government, 2024; Scottish Government, 2025a). Full enforcement of Low Emission Zones (LEZs) has now been extended across all four major Scottish cities, with early evaluations demonstrating substantial improvements in air quality. Monitoring data indicate a 34% reduction in nitrogen dioxide concentrations within Glasgow city centre following full LEZ enforcement between 2023 and 2024 (Glasgow City Council, 2025).

At a strategic level, the Scottish Government has initiated preparatory work towards a new Air Quality Delivery Framework for Scotland, planned to replace CAFS2 after 2026. In the UK, the Environment Act (2021) continues to drive legally binding commitments, including new, more ambitious PM₂.₅ targets for England.

Conclusion

The review, together with the wider international evidence base, demonstrates that low‑level air pollution continues to produce detectable adverse health effects and that further reductions in concentrations are likely to deliver measurable population health benefits. For policymakers and stakeholders, this reinforces the need to view air quality not simply as a matter of regulatory compliance, but as a continuing public health challenge, even in low‑pollution contexts.

References

Scottish Government (2023a) Health impacts of low‑level air pollution: review and assessment of the evidence. Edinburgh: Scottish Government. Available from:
https://www.gov.scot/publications/review-assessment-evidence-health-impacts-low-level-pollution-countries-levels-ambient-air-pollution-comparable-scotland/
[Last accessed 9 April 2026].

Scottish Government (2023b) Summary report: review and assessment of the evidence on health impacts of low‑level air pollution in countries with ambient concentrations comparable to Scotland. Edinburgh: Scottish Government. Available from: https://www.gov.scot/publications/summary-report-review-assessment-evidence-health-impacts-lowlevel-pollution-countries-levels-ambient-air-pollution-comparable-scotland/documents/
[Last accessed 9 April 2026].

Scottish Government (2024) Cleaner Air for Scotland 2 strategy: progress report. Edinburgh: Scottish Government. Available from:
https://www.gov.scot/publications/cleaner-air-scotland-2-strategy-progress-report/
[Last accessed 9 April 2026].

Scottish Government (2025a) Cleaner Air for Scotland 2 strategy: progress report. Edinburgh: Scottish Government. Available from:
https://www.gov.scot/publications/cleaner-air-scotland-2-strategy-progress-report-2/
[Last accessed 9 April 2026].

Scottish Government (2025b) Air quality policy update: Scottish Air Quality Annual Seminar 2025. Edinburgh: Scottish Government. Available from:
https://www.scottishairquality.scot/sites/default/files/publications/2025-04/Air_Quality_Policy_Update_Andrew_Taylor.pdf
[Last accessed 9 April 2026].

Glasgow City Council (2025) City centre air pollution drops by a third following LEZ enforcement. Available from:
https://www.glasgow.gov.uk/13535
[Last accessed 9 April 2026].

HM Government (2021) Environment Act 2021. London: The Stationery Office. Available from:
https://www.legislation.gov.uk/ukpga/2021/30/contents/enacted
[Last accessed 9 April 2026].

Department for Environment, Food & Rural Affairs (Defra) (2025a) Air pollution in the UK 2024: compliance assessment summary. London: Defra. Available from:
https://www.gov.uk/government/publications/air-pollution-in-the-uk-2024/air-pollution-in-the-uk-2024-compliance-assessment-summary
[Last accessed 9 April 2026].

Department for Environment, Food & Rural Affairs (Defra) (2025b) Air pollution in the UK 2024. London: Defra. Available from:
https://assets.publishing.service.gov.uk/media/68da4202c487360cc70c9e4f/air_pollution_uk_2024_issue_1.pdf
[Last accessed 9 April 2026].

World Health Organization (2021) WHO global air quality guidelines: particulate matter (PM₂.₅ and PM₁₀), ozone, nitrogen dioxide, sulphur dioxide and carbon monoxide. Geneva: World Health Organization. Available from:
https://www.who.int/publications/i/item/9789240034228
[Last accessed 9 April 2026].

Meet the CPWHB leadership team – introducing the Centre Director and Theme Leads

Posted on

By Dr. Issy Bray and Yarden Woolf

The Centre for Public Health and Wellbeing aims to impact directly on population health and wellbeing, to reduce health inequalities and enable ethical and reflexive contributions to public health policy and practice. Our approach is multidisciplinary and spans physical, health and social sciences.

Dr. Issy Bray is the Director of the Centre for Public Health and Wellbeing and Associate Professor in Public Health (Epidemiology). She has been with UWE Bristol for over 12 years and currently teaches on the Quantitative Health Research module and the Epidemiology of Non-Communicable Disease modules (MSc Public Health) as well as supervising PhD and MSc students.

The Global Public Health theme brings together innovative social science, health, and implementation research to address pressing population health challenges around the world. Current work includes research funded through the NIHR Global Health Research Programme in collaboration with the Nepal Injury Research Centre at Kathmandu Medical College, with projects exploring interdisciplinary approaches to road danger reduction and the cultural and sociological factors that influence injury risk and prevention in Nepal. The theme also includes research on migration and migrant integration, generating evidence that informs policy and supports progress toward global health equity.

Ageing Well is a brand-new theme for the Centre for Public Health and Wellbeing at UWE Bristol. The vision for this theme is to carry out and support inclusive, interdisciplinary and world-leading public health research that promotes healthy ageing including dementia across the life course underpinned by a socioecological approach to health and wellbeing. Emily has recently completed a qualitative study working closely with voluntary agencies in West Somerset and Cornwall to better understand the particular experiences and challenges of people living with dementia and their families living in rural and coastal communities.

Our research explores how the design of places can shape everyday behaviours, reduce risks, and improve health and wellbeing for communities. This includes looking at strategies for safer streets, stronger community safety, and better integration of health into planning decisions, while also seeking to reduce environmental impacts and improve population health and wellbeing. Emma is currently leading on a project tasked with creating guidance to help local planning authorities in England create healthier places for everyone through better integration of health into local planning policies.

This theme is essentially about creating communities where people can thrive. It brings together community groups, organisations, and networks with public, private, and non-governmental partners to drive social action and meaningful change. Building healthy communities demands a multidisciplinary lens spanning diverse topics such as urban planning, healthy ageing, and digital inclusion, while applying robust methodologies and evaluation design to generate high-quality evidence. Amy is currently working on a project which tackles the complex challenge of drug and alcohol dependency by exploring how individuals engage with community-based resources and what supports or hinders that connection.

Our work within this theme explores different approaches to and methodologies for public involvement and co-production, and what impact these can have. We have a particular focus on how the voice of those experiencing health inequalities can be meaningfully included in research prioritization, design and implementation, and what power-sharing can mean in practice. Jo recently led a project which co-produced resources for Black people living with stroke, following the ‘Experience-Based Co-design’ (EBCD) methodology. The project included the public as co-applicants and core team members, community researchers and co-design facilitators

The Public Health Economics and Evaluation theme focuses on generating robust, policy-relevant economic evidence to inform decision-making across public health, prevention, and integrated care. The theme leads the centre’s work on economic evaluation, return-on-investment modelling, realist economic evaluation, and capacity-building with local authorities and ICS partners, ensuring that our research translates into practical, scalable improvements in population health. A key project Hamad is involved in is the NIHR-funded realist evaluation and economic appraisal of how mosque-based health screening, education and prevention activities influence health and wellbeing in Muslim communities.

Back to top